PMID: Chem Biol Drug Des. 2021 Aug 19. Epub 2021 Aug 19. PMID: 34411455 Abstract Title: Sesamin exerts anti-tumor activity in esophageal squamous cell carcinoma via inhibition of TRIM44 and NF-κB signaling. Abstract: Tripartite motif-containing 44 (TRIM44) is known to play an oncogenic role in multiple human cancers, including esophageal cancer. Sesamin possesses potent anti-inflammatory…
Lycopene reduces cholesterol absorption and prevents atherosclerosis.
PMID: J Agric Food Chem. 2021 Sep 8 ;69(35):10114-10120. Epub 2021 Aug 25. PMID: 34428895 Abstract Title: Lycopene Reduces Cholesterol Absorption and Prevents Atherosclerosis in ApoEMice by Downregulating HNF-1α and NPC1L1 Expression. Abstract: Our previous study showed that lycopene reduced the absorption of cholesterol in Caco-2 cells through inhibiting Niemann-Pick C1-Like 1 (NPC1L1) expression. Herein,…
Therapeutic effect of Aegle marmelos fruit extract against DMBA induced breast cancer.
PMID:Â Sci Rep. 2020 10 22 ;10(1):18016. Epub 2020 Oct 22. PMID: 33093498 Abstract Title:Â Therapeutic effect of Aegle marmelos fruit extract against DMBA induced breast cancer in rats. Abstract:Â Breast cancer is among most common form of cancer worldwide. It is also the major cause of death in female cancer patient around the world….
BPA might increase the risk of breast cancer incidence.
PMID:Â Sci Rep. 2021 Sep 16 ;11(1):18411. Epub 2021 Sep 16. PMID: 34531470 Abstract Title:Â Bisphenol-A in biological samples of breast cancer mastectomy and mammoplasty patients and correlation with levels measured in urine and tissue. Abstract:Â Endocrine disrupting chemicals (EDCs) are organic compounds that have estrogenic activity and can interfere with the endocrine system. Bisphenol-A…
Passiflora edulis fruit peel extract could be used as an adjuvant for treating hypertension.
PMID:Â Planta Med. 2021 Aug 3. Epub 2021 Aug 3. PMID: 34344056 Abstract Title:Â Cardiovascular Effects Induced by Fruit Peels from Passiflora edulis in Hypertensive Rats and Fingerprint Analysis by HPLC-ESI-MSn spectrometry. Abstract:Â Hypertension is a chronic disease and a global health problem. Due to its high prevalence, it constitutes the most important risk factor…
Wuhan: Back to the Beginning, Where the Whole Fraud Started; Buried Revelations
What is being called COVID is not one disease. For the most part, it is a relabeling of older traditional lung conditions—flu, COPD, pneumonia, etc
Censorship and The Way Forward
The open sharing of information is essential. More important, though, is our approach to sharing. Most important is to empower people to trust themselves and express the need to unify with others
Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression.
PMID:Â Aging (Albany NY). 2021 07 27 ;13(14):18392-18403. Epub 2021 Jul 27. PMID: 34314383 Abstract Title:Â Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression via JAK1/STAT3 signaling. Abstract:Â Psoriasis is a chronic inflammatory skin disease characterized by abnormal proliferation and differentiation of keratinocytes. Since curcumol exhibits anti-inflammatory properties in various…
Anticancer effects of cinnamaldehyde through Inhibition of ErbB2/HSF1/LDHA pathway in 5637 cell line of bladder cancer.
PMID:Â Anticancer Agents Med Chem. 2021 Jul 26. Epub 2021 Jul 26. PMID: 34315398 Abstract Title:Â Anticancer Effects of Cinnamaldehyde through Inhibition of ErbB2/HSF1/LDHA Pathway in 5637 Cell Line of Bladder Cancer. Abstract:Â BACKGROUND: The growing prevalence of bladder cancer worldwide has become a major concern for the researchers, and the side effects of chemotherapy…
Neurorescue effects of frondoside A and ginsenoside Rg3 in C. elegans model of Parkinson’s disease.
PMID: Molecules. 2021 Aug 10 ;26(16). Epub 2021 Aug 10. PMID: 34443430 Abstract Title: Neurorescue Effects of Frondoside A and Ginsenoside Rg3 inModel of Parkinson’s Disease. Abstract: Parkinson’s disease (PD) is a currently incurable neurodegenerative disorder characterized by the loss of dopaminergic (DAergic) neurons in the substantia nigra pars compacta andα-synuclein aggregation. Accumulated evidence indicates…
