Category: Natural Health

Sesamin exerts anti-tumor activity in esophageal squamous cell carcinoma via inhibition of TRIM44 and NF-κB signaling.

Sesamin exerts anti-tumor activity in esophageal squamous cell carcinoma via inhibition of TRIM44 and NF-κB signaling.

PMID:  Chem Biol Drug Des. 2021 Aug 19. Epub 2021 Aug 19. PMID: 34411455 Abstract Title:  Sesamin exerts anti-tumor activity in esophageal squamous cell carcinoma via inhibition of TRIM44 and NF-κB signaling. Abstract:  Tripartite motif-containing 44 (TRIM44) is known to play an oncogenic role in multiple human cancers, including esophageal cancer. Sesamin possesses potent anti-inflammatory…

Lycopene reduces cholesterol absorption and prevents atherosclerosis.

Lycopene reduces cholesterol absorption and prevents atherosclerosis.

PMID:  J Agric Food Chem. 2021 Sep 8 ;69(35):10114-10120. Epub 2021 Aug 25. PMID: 34428895 Abstract Title:  Lycopene Reduces Cholesterol Absorption and Prevents Atherosclerosis in ApoEMice by Downregulating HNF-1α and NPC1L1 Expression. Abstract:  Our previous study showed that lycopene reduced the absorption of cholesterol in Caco-2 cells through inhibiting Niemann-Pick C1-Like 1 (NPC1L1) expression. Herein,…

BPA might increase the risk of breast cancer incidence.

BPA might increase the risk of breast cancer incidence.

PMID:  Sci Rep. 2021 Sep 16 ;11(1):18411. Epub 2021 Sep 16. PMID: 34531470 Abstract Title:  Bisphenol-A in biological samples of breast cancer mastectomy and mammoplasty patients and correlation with levels measured in urine and tissue. Abstract:  Endocrine disrupting chemicals (EDCs) are organic compounds that have estrogenic activity and can interfere with the endocrine system. Bisphenol-A…

Passiflora edulis fruit peel extract could be used as an adjuvant for treating hypertension.

Passiflora edulis fruit peel extract could be used as an adjuvant for treating hypertension.

PMID:  Planta Med. 2021 Aug 3. Epub 2021 Aug 3. PMID: 34344056 Abstract Title:  Cardiovascular Effects Induced by Fruit Peels from Passiflora edulis in Hypertensive Rats and Fingerprint Analysis by HPLC-ESI-MSn spectrometry. Abstract:  Hypertension is a chronic disease and a global health problem. Due to its high prevalence, it constitutes the most important risk factor…

Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression.

Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression.

PMID:  Aging (Albany NY). 2021 07 27 ;13(14):18392-18403. Epub 2021 Jul 27. PMID: 34314383 Abstract Title:  Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression via JAK1/STAT3 signaling. Abstract:  Psoriasis is a chronic inflammatory skin disease characterized by abnormal proliferation and differentiation of keratinocytes. Since curcumol exhibits anti-inflammatory properties in various…

Anticancer effects of cinnamaldehyde through Inhibition of ErbB2/HSF1/LDHA pathway in 5637 cell line of bladder cancer.

Anticancer effects of cinnamaldehyde through Inhibition of ErbB2/HSF1/LDHA pathway in 5637 cell line of bladder cancer.

PMID:  Anticancer Agents Med Chem. 2021 Jul 26. Epub 2021 Jul 26. PMID: 34315398 Abstract Title:  Anticancer Effects of Cinnamaldehyde through Inhibition of ErbB2/HSF1/LDHA Pathway in 5637 Cell Line of Bladder Cancer. Abstract:  BACKGROUND: The growing prevalence of bladder cancer worldwide has become a major concern for the researchers, and the side effects of chemotherapy…

Neurorescue effects of frondoside A and ginsenoside Rg3 in C. elegans model of Parkinson’s disease.

Neurorescue effects of frondoside A and ginsenoside Rg3 in C. elegans model of Parkinson’s disease.

PMID:  Molecules. 2021 Aug 10 ;26(16). Epub 2021 Aug 10. PMID: 34443430 Abstract Title:  Neurorescue Effects of Frondoside A and Ginsenoside Rg3 inModel of Parkinson’s Disease. Abstract:  Parkinson’s disease (PD) is a currently incurable neurodegenerative disorder characterized by the loss of dopaminergic (DAergic) neurons in the substantia nigra pars compacta andα-synuclein aggregation. Accumulated evidence indicates…

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