Neurochem Res. 2020 Oct ;45(10):2278-2285. Epub 2020 Jul 16. PMID: 32676948
Neuroprotective Effect Of Peptide Fractions from Chia (Salvia hispanica) on HO-Induced Oxidative Stress-Mediated Neuronal Damage on N1E-115 Cell Line.
Neurodegenerative diseases (ND) affect around a billion people worldwide. Oxidative stress plays a critical role in the activation of neuronal death mechanisms, implicated in the ND etiology. In the present research, the neuroprotective effect of the S. hispanica protein derivatives is evaluated, on neuronal cells N1E-115, after the damage induction with HO. From the protein-rich fraction of S. hispanica, three peptide fractions were obtained (3-5, 1-3 y