Photobiomodulation therapy applied at two moments 6h before and immediately before exercise was able to produce the same total work with lower fatigue.


Photobiomodul Photomed Laser Surg. 2020 Nov 24. Epub 2020 Nov 24. PMID: 33232629

Abstract Title: 

Dose-Response Effect of Photobiomodulation Therapy on Muscle Performance and Fatigue During a Multiple-Set Knee Extension Exercise: A Randomized, Crossover, Double-Blind Placebo-Controlled Trial.


The aim of this study was to identify the best energy dose of photobiomodulation therapy (PBMT) able to improve muscle performance and reduce fatigue during multiple-set knee extension exercise.Eighteen physically active men participated in this study. Each participant performed an isokinetic exercise protocol (5 sets of 10 knee extension repetitions, maximum contractions at 60°·s) in 6 sessions, 1 week apart. Control condition (no PBMT/placebo treatments) was applied at the first and sixth sessions. Placebo or PBMT with 135, 270, or 540 J/quadriceps was randomly applied from the second to fifth sessions. Placebo/PBMT treatments were always applied at two moments: 6 h before and immediately before exercise. The isometric and isokinetic concentric peak torques were assessed before and after the exercise protocol.The knee extension exercise performance (total work performed during exercise) was not affected by PBMT (135, 270, and 540 J) compared with placebo treatment. However, all PBMT treatments (135, 270, and 540 J) led to lower percentage drop compared with placebo and control conditions on isometric peak torque (IPT), concentric peak torque (CPT), and concentric work (W). All PBMT doses led to possibly positive or likely positive effects on IPT, CPT, and W compared with placebo.Our findings demonstrate that PBMT with 135, 270, and 540 J applied at two moments (6 h before and immediately before exercise) was able to produce the same total work with lower fatigue, which may facilitate the performance of additional sets (i.e., higher training volume).

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