The National Health Service had a difficult birth 70 years ago. Many GPs did not want to be part of it, fearing they would lose their independence and a patient/doctor relationship, but at a time when many sick people could not afford medical treatment the NHS seem to be a beacon of enlightenment for the…
Isoalantolactone induces reactive oxygen species mediated apoptosis in pancreatic carcinoma PANC-1 cells.
PMID: Int J Biol Sci. 2012 ;8(4):533-47. Epub 2012 Mar 28. PMID: 22532787 Abstract Title: Isoalantolactone induces reactive oxygen species mediated apoptosis in pancreatic carcinoma PANC-1 cells. Abstract: Isoalantolactone, a sesquiterpene lactone compound possesses antifungal, antibacteria, antihelminthic and antiproliferative activities. In the present study, we found that isoalantolactone inhibits growth and induces apoptosis in pancreatic…
Editor Tested: The Big Guide to Bed-in-Box Mattresses
Let’s appreciate for a moment that we now live in a world where, with the click of a button, you can have a mattress delivered right to your doorstep in a few business days. The only problem (if you can even call it that) is figuring out which is the best bed in a box…
Alantolactone selectively suppresses STAT3 activation and exhibits potent anticancer activity in MDA-MB-231 cells.
PMID: Cancer Lett. 2015 Feb 1 ;357(1):393-403. Epub 2014 Nov 27. PMID: 25434800 Abstract Title: Alantolactone selectively suppresses STAT3 activation and exhibits potent anticancer activity in MDA-MB-231 cells. Abstract: The important goal of cancer drug discovery is to develop therapeutic agents that are effective, safe, and affordable. In the present study, we demonstrated that alantolactone,…
The Best Way To Keep Your Bread Fresh for Longer Is Not What You Think
Even with the vast number of delicious meals you can make with bread—fluffy French toast, avocado toast, paninis—chances are that you aren’t going through a whole loaf in the span of a couple of days unless you’re cooking for a whole household of people. And if you’ve ever tried making a sandwich with stale bread,…
Inhibition of growth of esophageal cancer by alantolactone.
PMID: Anticancer Agents Med Chem. 2021 Jan 12. Epub 2021 Jan 12. PMID: 33438562 Abstract Title: Inhibition of Growth of Esophageal Cancer by Alantolactone via Wnt/βCatenin Signaling. Abstract: BACKGROUND: Alantolactone (AL) is a natural compound extracted from the roots of Inula Helenium L, which exerts an antitumor effect in a variety of cancer cell lines;…
These Drugs May Be A Necessary Evil: Here’s What To Do About It
I woke suddenly at 2 a.m. with my heart pounding in my chest. My 30 years of experience as a physician instantly told me something was seriously wrong. I woke my wife up and said, “I think we need to get to the ER.” Thirty minutes later, I was looking up at an emergency room…